Webb1 juli 2008 · These observations strongly suggest that Sin3B plays an essential role in coordinating the chromatin modifying activities required for the transient repression of pro-proliferation genes in... Webb11 nov. 2014 · SIN3B, the SASP, and pancreatic cancer Cellular senescence is classically considered a tumor suppressive mechanism. In addition to having stably exited the cell …
Expression of SIN3B in cancer - Summary - The Human Protein Atlas
Webb8 aug. 2014 · As Sin3b is also required for transcriptional repression by Mxd-Max complexes, our results suggest that, at least in some cell types, Sin3b limits Myc activity … Webb1 jan. 2016 · Sin3A/B are global transcription regulators that provide a versatile platform for diverse chromatin-modifying activities. Sin3 proteins regulate key cellular functions that include cell cycle, proliferation, and differentiation, and have recently been implicated in cancer pathogenesis. bioluminescence beach nitk
Chromatin-Associated Protein SIN3B Prevents Prostate Cancer …
WebbExpression of SIN3B (KIAA0700) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability … Webb5 jan. 2024 · Sin3B is required for the competitive repopulation capacity of HSCs. (A) Schematic for serial competitive repopulation assay. ... E2F4, and the pocket proteins Rb1, p107, and p130. 32 Work in cancer cell lines and fibroblasts demonstrated that Sin3B, along with HDAC1, ... Webb1 apr. 2007 · Sin3B expression is required for cellular senescence and is up-regulated upon oncogenic stress. 23: 24691445: 2014: Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression. 21: 20547842: 2010: Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer … daily paediatric data input form