4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain. 4T1 cells are epithelial and are resistant to 6-thioguanine. In preclinical research, 4T1 cells have been used to study breast cancer metastasis as they can metastasize to the lung, liver, lymph nodes, brain and bone. The … See more 4T1 cell line was originally isolated by Fred Miller and colleagues as one of four sublines derived from the 410.4 tumor that was isolated from a single spontaneously arising mammary tumor. See more 4T1 resembles human metastatic triple-negative breast cancer (TNBC) in lack of the expression of estrogen receptor (ER), progesterone receptor (PR) See more 4T1 cells grow in 37 °C with 95% air and 5% of carbon dioxide (CO 2). Their average doubling time is 14 hours. The base medium for this cell … See more To understand the pathogenesis of cancer patients, it is necessary to have model systems that faithfully mimic this condition. The application of a murine cancer cell line, such as 4T1, … See more • Cellosaurus entry for 4T1 See more Web普诺赛生物(Procell),您身边的细胞培养专家,顶级细胞供应商,为您提供细胞系、原代细胞、肿瘤细胞、正常细胞、耐药细胞、抗性细胞、细胞株供应、进口细胞株、细胞株 …
阿霉素抗4T1乳腺癌荷瘤小鼠的免疫调控机制
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Web4t1-诱导的肿瘤在手术后及未手术情况下转移的动力学相近,可以用作手术后及未手术模型。跟其他肿瘤模型相比,由于4t1的抗6-硫鸟噙特性,微小的转移细胞团(少到仅仅1个)也可 … WebJun 26, 2014 · Popular answers (1) Indeed 4T1 is an aggressively growing tumor. Mice generally succumb to metastasis or asphyxiation arising from the increased numbers of circulating white blood cells. That said ... Web1.4t1细胞生长速度快,细胞汇合度越高越难消化,建议分次消化。 一次消化至有细胞移动漂浮时终止,再进行二次消化剩余的细胞,尽量消化成单颗细胞,4T1细胞传代第二天有少 … scouts investiture